WEBVTT	#Elemental Media Engine(TM) 2.17.1.0

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Denmark's Novo Nordisk
-Ablynx.

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We are launching our
once-weekly GLP-1,

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Ozempic in the US
market. We also have a

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big obesity business.

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We will continuously
roll out our innovative

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portfolio of GLP-1s.

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Here's a two-week chart
of the S & P.

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But 2500 would be an
important support

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And sales surge at Novo
Nordisk.

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level.

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The CEO says the firm
is seeing a gradual

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recovery in patients
initiating diabetes

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treatment. They also
have a recently

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approved drug for
weight loss with really

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extreme results.

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So how does Wegovy
help you lose weight?

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We have a very
efficacious product now

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on the market in the
US. Wegovy.

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Novo was the only
company with FDA

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approval to market
Wegovy.

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Other than the fact
that that chart's about

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the greatest chart
you've ever seen and

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that's all about one
drug mostly, David.

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It's a drug called
Wegovy.

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A new blockbuster
obesity drug Wegovy.

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Novo Nordisk.

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Ozempic and Wegovy.
Shares of Novo Nordisk

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are up sharply this
morning. That the

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weight loss drug
Wegovy. Novo Nordisk.

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Here's a headline
Dethroning LVMH as

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Europe's most valuable
company thanks to

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Wegovy.

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Well, here it is
Saturday morning.

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It's the day that I
give myself my Ozempic

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injection. This is my
box of Ozempic.

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This is 65 year old
Mary Tripp.

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She's struggled with
her weight since she

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was 11 years old.

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I did have times in my
life where, um, you

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know, it was hard for
me to get out and take

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a walk or get out and
do anything.

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I mean, it was, you
know, and at those

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times, yes. I mean, I
felt like a failure.

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While a gastric bypass
operation in 2005

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reversed her Type 2
diabetes, the weight

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wouldn't stay off
until summer 2022 when

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her doctor recommended
she try Ozempic.

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We tried different
diabetes drugs that,

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you know, that also
help you lose weight.

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But there was a
several of the older

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ones that I was
allergic to.

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So then it had been a
number of years and,

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and you know, I was
kind of saying to her

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like, is there
anything else we can

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do? And she said, Why
don't we try Ozempic

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and see how that goes.

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Her diabetes made her a
prime candidate for the

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drug. She's lost about
60 pounds since June

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2022. Results like
Mary's are part of why

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there's a global surge
in demand for

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Semaglutide sold under
the name Ozempic for

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patients with diabetes
and Wegovy for those

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seeking weight loss.

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In 2021, national
spending for

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Semaglutide totaled
$10.7 billion.

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Danish pharmaceutical
company Novo Nordisk

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developed it,
transforming an

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untapped industry and
likely the company's

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fortunes forever.

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This is going to be one
of the biggest, the

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highest demand drugs
in the history of

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pharmaceuticals.

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While diabetes drugs
have been effective for

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decades, drugs for
weight loss have not.

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And the potential
impact is huge.

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More than 1 billion
people suffer from

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obesity worldwide.

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It's been a crazy ride
and it's it's still

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ongoing. It's clear
that nobody had

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expected that it would
be taking off this

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In September 2023,
CNBC's Melissa Lee got

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quickly.

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an inside look at a
Novo Nordisk lab in

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Denmark. Novo Nordisk
didn't set out to

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create a weight loss
drug. It was an

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unintentional side
effect discovered while

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studying GLP-1s.

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We had no clue about
this molecule, will

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come out with higher
efficacy than our past

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versions of of these
molecules.

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Semaglutide is the
medical name for

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Ozempic and Wegovy and
falls under a class of

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drugs called GLP-1
agonists.

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GLP-1 drugs mimic
GLP-1 molecules in the

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body and regulate
blood sugar, stimulate

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insulin production and
suppress appetite.

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I guess that's what
I've been looking for

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is something that will
like tell my brain you

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really don't need this
and you really don't

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want it.

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We knew we had a type
two diabetes product,

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but we also talked
about if it actually

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works in obesity, do
we dare to go in and do

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that development?

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As it often plays out
in research, there's

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also some surprises on
the way.

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Semaglutide was
developed in the early

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2000s and released in
2012 as Ozempic a

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weekly injection for
those with Type 2

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diabetes. It passed
FDA approval in 2017.

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Wegovy was approved in
2021.

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Neither were an
immediate hit.

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Weight loss drugs
already in the market

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weren't as effective,
which made it

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challenging when
trying to promote to

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those disillusioned
with the diet industry.

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Many who live with
obesity have tried a

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lot of different
things and often

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failed. So actually,
just mobilizing

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patients to seek care
is is not easy.

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It was not a huge
success, so to say.

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Doctors say demand took
off when fear about

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death was spreading
during the Covid-19

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pandemic. According to
the Centers for Disease

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Control and
Prevention, obesity

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could triple the risk
of hospitalization.

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That was the moment
that everything

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shifted. I remember
having patients coming

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to me, patients with
obesity or struggling

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with weight,
specifically saying, I

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don't want to die from
Covid due to my weight.

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In 2020, more than a
million US patients

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were prescribed
Semaglutide. In 2021,

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that number jumped to
about 2 million.

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They didn't see it
coming. No one saw it

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come. Investors didn't
and analysts didn't.

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This one drug alone
could be worth 200 $300

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billion over time.

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I think we were maybe 6
to 10 people working on

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that project. 6 to 10
people in the lab like

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this? Yeah, we were in
different labs.

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Pow Bloch was one of
the scientists in the

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early phases of
Semaglutide's

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discovery.

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I made a Semaglutide
the first time in 2004,

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so it was a long
process before we hit

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the right one.

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But Novo Nordisk's
100-year history began

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with the desire to
cure diabetes, as one

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of the company's
founders had the

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disease. In 1922, a
group of scientists

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traveled to Canada to
bring back a new

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miracle drug insulin
to Scandinavia, leading

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to the founding of
Nordisk

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InsulinLaboratorium.

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Less than three months
later, they treated the

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first ten patients.

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And they didn't have
anything at all when

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they started. It was
made in a basement.

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A few years later, two
former Nordisk

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employees started
their own company, Novo

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Therapeutic. Novo
Nordisk competed as the

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world's leading
insulin producers until

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finally merging in
1989 to become Novo

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Nordisk.

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They saw this
competition on a

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transatlantic
perspective and

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globally, and there
were huge demands for

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investments in
development and

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research.

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In August 2023, the
company became Europe's

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most valuable company
by market cap, more

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valuable than its home
country. Denmark's

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total economy, its
second quarter earnings

00:07:05.825 --> 00:07:07.160
in 2023, followed
suit.

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The company reported a
46% increase in net

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profits and a 32%
increase in sales

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compared to the same
quarter the year prior.

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Sales of Ozempic and
Wegovy rose by 58% and

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363% respectively in
the first six months of

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2023. And in the same
period, the company

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recorded overall net
sales of $15.1 billion.

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To put that in
perspective, the year

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Novo Nordisk developed
Semaglutide in 2012,

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the company's full
year net sales were

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$13.5 billion.

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In the past five
years, the share price

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of Novo Nordisk has
more than quadrupled.

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The stock sold for
$89.99 as of October

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5th, 2023.

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We haven't seen any
performance even close

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to this.

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Just days prior to
second quarter earnings

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in 2023, it was
reported that a late

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stage clinical trial
showed Wegovy reduced

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the risk of
cardiovascular events

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like heart attacks or
strokes by 20% compared

00:08:02.882 --> 00:08:06.853
to a placebo. Shares
soared by 17% that day.

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The select trial
exceeded expectations

00:08:09.355 --> 00:08:10.857
and helped the company
showcase the drug's

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potential beyond its
image as a vanity drug.

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We all saw that, okay,
this is not just about

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weight.

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The select trial was
really, you know, one

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of the bigger moments,
I believe, in health

00:08:21.133 --> 00:08:23.736
care over the past few
years, aside from Covid

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vaccines. And if these
data stick over the

00:08:27.607 --> 00:08:30.476
long term, we can come
up with numbers that we

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just have not seen for
other therapeutics.

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The company raised its
full year profit and

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sales forecasts for a
second time.

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We felt comfortable all
along that dealing with

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obesity is actually
leading to a number of

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health benefits. So
far, we have developed

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it for Type 2 diabetes
and obesity.

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We are testing it out
also in Alzheimer's.

00:08:50.997 --> 00:08:53.165
One of the reasons why
it works in obesity is

00:08:53.266 --> 00:08:54.700
that it deals with
your craving.

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So you say addiction
for for food.

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There are some
speculations that close

00:08:59.539 --> 00:09:01.741
to that center in the
brain is also the

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control of other
addictions.

00:09:03.175 --> 00:09:05.144
While the company
continues to diversify

00:09:05.244 --> 00:09:08.581
its portfolio, at the
moment, it is all in on

00:09:08.681 --> 00:09:10.750
obesity care. Later in
August, the company

00:09:10.850 --> 00:09:12.852
acquired competitor
embark biotech for

00:09:12.952 --> 00:09:17.456
$16.3 million up front
and up to $498 million

00:09:17.557 --> 00:09:19.892
in milestone payments
and drug developer

00:09:19.992 --> 00:09:23.296
inverse Argo Pharma
for about $1 billion.

00:09:30.603 --> 00:09:33.306
More than 100 million
US adults are living

00:09:33.406 --> 00:09:36.542
with obesity. In its
2020 report, the Milken

00:09:36.642 --> 00:09:38.544
Institute found that
the economic and social

00:09:38.644 --> 00:09:41.280
impacts of the disease
in the US alone account

00:09:41.380 --> 00:09:43.082
for nearly $1.4
trillion.

00:09:44.250 --> 00:09:46.719
Its estimated annual
medical US costs were

00:09:46.819 --> 00:09:49.388
nearly $173 billion in
2019.

00:09:51.223 --> 00:09:53.559
Type 2 diabetes and
obesity go hand in

00:09:53.659 --> 00:09:55.461
hand. So by improving
one, we improve the

00:09:55.561 --> 00:09:57.964
other one, right? But
if we look at it in the

00:09:58.064 --> 00:10:01.500
obesity weight loss
side, we are preventing

00:10:01.601 --> 00:10:04.203
Type 2 diabetes by
treating obesity.

00:10:04.337 --> 00:10:07.306
Yet obesity is largely
an untapped market.

00:10:07.406 --> 00:10:09.675
Prior to GLP 1s,
previous weight loss

00:10:09.775 --> 00:10:11.377
drugs were either
ineffective or had

00:10:11.477 --> 00:10:13.245
dangerous side
effects, like the diet

00:10:13.346 --> 00:10:15.615
drug combo Fen-Phen in
the 90s that was linked

00:10:15.715 --> 00:10:18.351
to heart and lung
damage in clinical

00:10:18.451 --> 00:10:20.419
trials, Wegovy was
shown to reduce body

00:10:20.519 --> 00:10:23.322
weight in people with
a BMI of 27 or greater

00:10:23.422 --> 00:10:25.491
by around 15%.

00:10:25.591 --> 00:10:27.493
There's always been a
barrier to break

00:10:27.593 --> 00:10:30.296
through weight loss of
about 10%.

00:10:30.396 --> 00:10:32.231
That's always been the
view that once you

00:10:32.331 --> 00:10:34.700
break through 10%,
this becomes a very,

00:10:34.800 --> 00:10:35.735
very real market.

00:10:35.835 --> 00:10:40.339
And Novo achieved
that, frankly, with

00:10:40.439 --> 00:10:40.673
While Novo Nordisk is a
first mover in obesity

00:10:40.773 --> 00:10:43.075
Wegovy.

00:10:43.175 --> 00:10:44.944
care, the company
can't solve the

00:10:45.044 --> 00:10:47.813
epidemic alone. There
are 1 billion people

00:10:47.913 --> 00:10:49.448
suffering worldwide.

00:10:49.682 --> 00:10:53.452
To be able to support
all of the patients who

00:10:53.552 --> 00:10:56.022
are diagnosed or who
would be diagnosed as

00:10:56.122 --> 00:10:58.357
obese in the US
market, you'd have to

00:10:58.457 --> 00:11:01.293
be able to supply over
50 billion pens.

00:11:01.394 --> 00:11:04.163
That's a pretty
daunting task just to

00:11:04.263 --> 00:11:04.997
manufacture the
devices.

00:11:05.698 --> 00:11:08.868
In 2032, Novo Nordisk's
Semaglutide patent

00:11:08.968 --> 00:11:10.436
expires in the US.

00:11:10.536 --> 00:11:11.137
Many other
pharmaceutical

00:11:11.704 --> 00:11:14.140
companies are joining
the race by developing

00:11:14.240 --> 00:11:17.309
their own GLP-1 drugs
like Eli Lilly, which

00:11:17.410 --> 00:11:19.378
analysts say is Novo
Nordisk's biggest

00:11:19.478 --> 00:11:20.246
competitor.

00:11:20.346 --> 00:11:22.715
Amgen and Pfizer are
also working on

00:11:22.815 --> 00:11:23.849
products there.

00:11:23.949 --> 00:11:25.418
There's a number of
other companies,

00:11:25.518 --> 00:11:29.655
including Viking and
Structure on the small

00:11:29.755 --> 00:11:32.124
cap biotech side that
are vying for

00:11:32.224 --> 00:11:33.092
positioning here as
well.

00:11:33.659 --> 00:11:36.595
Eli Lilly's Tirzepatide
sold as Manjaro is more

00:11:36.696 --> 00:11:39.065
effective and boosts
higher weight loss

00:11:39.165 --> 00:11:41.333
results than
Semaglutide. Unlike

00:11:41.434 --> 00:11:44.303
Wegovy, Manjaro is not
yet FDA-approved for

00:11:44.403 --> 00:11:46.572
weight loss, but
expected to be in late

00:11:46.672 --> 00:11:48.974
2023 or early 2024.

00:11:49.075 --> 00:11:51.277
I like competition
because if there's no

00:11:51.377 --> 00:11:54.880
competition, there is
a risk that we do not

00:11:54.980 --> 00:11:57.383
stay innovative. So we
have been competing

00:11:57.483 --> 00:11:59.285
with Eli Lilly for 100
years.

00:12:05.157 --> 00:12:07.493
While growth has been
explosive, there are

00:12:07.593 --> 00:12:08.828
some concerns.

00:12:08.928 --> 00:12:11.397
For one, massive
demand for both Ozempic

00:12:11.497 --> 00:12:14.066
and Wegovy has caused
real supply shortages.

00:12:14.166 --> 00:12:15.868
The company is
expanding production

00:12:15.968 --> 00:12:18.604
capacity in its North
Carolina and Denmark

00:12:18.704 --> 00:12:19.638
facilities.

00:12:19.739 --> 00:12:22.007
If you look at just the
growth of go in the US,

00:12:22.108 --> 00:12:24.977
it's, you know, it's
more than doubling year

00:12:25.077 --> 00:12:27.079
over year. So more and
more capacity is coming

00:12:27.179 --> 00:12:27.980
in line.

00:12:28.080 --> 00:12:30.349
Off-label use is
another consideration.

00:12:30.449 --> 00:12:32.184
Everybody looks so
great. When I look

00:12:32.284 --> 00:12:34.186
around this room, I
can't help but wonder

00:12:34.286 --> 00:12:35.788
is Ozempic right for
me?

00:12:37.590 --> 00:12:40.226
As Jimmy Kimmel joked
at the 2023 Oscars,

00:12:40.326 --> 00:12:42.128
celebrities are
reportedly using these

00:12:42.228 --> 00:12:44.430
drugs to lose a few
extra pounds.

00:12:44.530 --> 00:12:46.766
They wouldn't be the
first. A recent study

00:12:46.866 --> 00:12:49.435
by data analytics firm
Trilliant Health found

00:12:49.535 --> 00:12:51.670
that only a little
more than half of US

00:12:51.771 --> 00:12:54.140
patients on GLP-1
drugs have a history of

00:12:54.240 --> 00:12:56.575
Type 2 diabetes or
received a prescription

00:12:56.675 --> 00:12:58.077
after a medical visit.

00:12:58.811 --> 00:13:01.247
It's a challenging
situation because it's

00:13:01.347 --> 00:13:03.816
a it's a new situation
for us.

00:13:03.916 --> 00:13:06.051
It's something we
cannot control.

00:13:06.152 --> 00:13:08.087
So we are really
doubling down in making

00:13:08.187 --> 00:13:11.490
sure that physicians
are educated around our

00:13:11.590 --> 00:13:12.491
products.

00:13:12.591 --> 00:13:14.593
But some experts don't
necessarily see off

00:13:14.693 --> 00:13:17.296
label use as an issue
and rather a challenge

00:13:17.396 --> 00:13:19.532
to solve for the
future. After treatment

00:13:19.632 --> 00:13:21.000
becomes available for
those who need it

00:13:21.100 --> 00:13:23.135
most, the next step is
likely reaching the

00:13:23.235 --> 00:13:25.304
average consumer. That
is, people who want to

00:13:25.404 --> 00:13:26.238
lose a little extra
weight.

00:13:26.639 --> 00:13:31.510
Consumer products don't
command the same profit

00:13:31.610 --> 00:13:33.412
margins that
pharmaceutical products

00:13:33.512 --> 00:13:37.082
do. But in terms of
being able to scale

00:13:37.183 --> 00:13:39.218
into a market, this
vast- The ability to

00:13:39.318 --> 00:13:42.588
kind of take this to
the consumer, assuming

00:13:42.688 --> 00:13:45.624
that we continue to
see good safety of this

00:13:45.724 --> 00:13:49.195
category over time,
would be potentially a

00:13:49.295 --> 00:13:51.931
next leg of the story,
not just for Novo

00:13:52.031 --> 00:13:54.300
Nordisk, but also for
the industry.

00:13:54.400 --> 00:13:57.937
If they can't innovate
successfully beyond

00:13:58.037 --> 00:14:00.439
Semaglutide, that's a
fundamental problem for

00:14:00.539 --> 00:14:02.274
the pharmaceutical
industry that they have

00:14:02.374 --> 00:14:03.142
to solve for.

00:14:03.242 --> 00:14:05.044
There are some
questions about side

00:14:05.144 --> 00:14:07.313
effects. Many users
have reported

00:14:07.413 --> 00:14:09.815
experiencing minor
symptoms like nausea.

00:14:09.915 --> 00:14:13.252
Others more serious,
like stomach paralysis,

00:14:13.352 --> 00:14:16.155
depression and
suicidal thoughts.

00:14:16.288 --> 00:14:19.024
On October 5th, 2023,
a study, the first of

00:14:19.124 --> 00:14:21.594
its kind, found an
increased risk of

00:14:21.694 --> 00:14:23.996
gastrointestinal
issues stemming from

00:14:24.096 --> 00:14:25.598
GLP -1 drugs.

00:14:25.798 --> 00:14:27.967
The Danish drugmaker,
along with Eli Lilly,

00:14:28.067 --> 00:14:30.135
was already facing a
lawsuit over what

00:14:30.236 --> 00:14:32.805
plaintiffs say is a
failure to disclose

00:14:32.905 --> 00:14:33.706
these types of health
issues.

00:14:34.874 --> 00:14:37.910
Any report of a safety
issue is, of course of

00:14:38.010 --> 00:14:39.979
concern because
patient safety is is

00:14:40.079 --> 00:14:42.381
fundamental. We
collect all these these

00:14:42.481 --> 00:14:45.351
data and we look at
all the clinical data

00:14:45.451 --> 00:14:48.287
we have. Each and
every safety report is

00:14:48.387 --> 00:14:51.457
investigated. We feel
that we have a robust

00:14:51.557 --> 00:14:54.293
data set and we share
that with the

00:14:54.393 --> 00:14:57.129
authorities who do
investigate this.

00:14:57.229 --> 00:15:00.199
But we believe that
there is no concerns

00:15:00.299 --> 00:15:02.601
besides what is
already established in

00:15:02.701 --> 00:15:03.002
And while those effects
aren't widespread, they

00:15:03.102 --> 00:15:04.803
the label.

00:15:04.904 --> 00:15:06.605
could derail the
company's growth.

00:15:06.705 --> 00:15:09.441
You could go all the
way back to 2003, 2004

00:15:09.541 --> 00:15:13.245
with Vioxx, Celebrex
and Bextra, the Cox two

00:15:13.345 --> 00:15:15.381
inhibitors, where
those products were

00:15:15.481 --> 00:15:19.051
projected to be 15 to
$20 billion market, it

00:15:19.151 --> 00:15:23.022
actually ended up sort
of reversing and going

00:15:23.122 --> 00:15:25.591
back to, you know, a
$3 billion market.

00:15:25.691 --> 00:15:27.159
Do we think that's
going to happen here?

00:15:27.259 --> 00:15:28.427
Absolutely not.

00:15:28.527 --> 00:15:30.663
For Mary, so far, side
effects aren't a

00:15:30.763 --> 00:15:31.497
concern.

00:15:32.665 --> 00:15:33.899
A negative.

00:15:34.133 --> 00:15:35.200
Like whatever.

00:15:35.301 --> 00:15:37.002
If I'm still around in
20 years, I'll be

00:15:37.102 --> 00:15:37.903
thrilled.

00:15:38.837 --> 00:15:40.306
What is an issue?

00:15:40.406 --> 00:15:41.607
Price.

00:15:41.707 --> 00:15:45.311
Pens cost about $1000
to $1300 a month out of

00:15:45.411 --> 00:15:48.047
pocket and if used
correctly, should be

00:15:48.147 --> 00:15:49.748
taken indefinitely.

00:15:49.848 --> 00:15:52.751
As of 2023, Medicare
does not cover Wegovy

00:15:52.918 --> 00:15:55.487
and only some plans
fully cover Ozempic and

00:15:55.587 --> 00:15:57.723
Mounjaro for
diabetics; putting

00:15:57.823 --> 00:16:00.125
another barrier
between US users and

00:16:00.225 --> 00:16:01.226
the drugs.

00:16:01.393 --> 00:16:04.229
We have a situation
where there's a very

00:16:04.363 --> 00:16:06.432
steep demand and we
cannot meet that

00:16:06.532 --> 00:16:08.667
demand. And I can only
think about what it

00:16:08.767 --> 00:16:10.235
would mean if we start
giving it away.

00:16:10.336 --> 00:16:11.470
So we cannot do that.

00:16:11.570 --> 00:16:14.006
But that too could
change as society's

00:16:14.106 --> 00:16:16.241
understanding of
obesity evolves.

00:16:16.342 --> 00:16:18.644
The American Medical
Association officially

00:16:18.744 --> 00:16:21.580
recognized obesity as
a disease in 2013.

00:16:21.680 --> 00:16:23.816
American Medical
Association is changing

00:16:23.916 --> 00:16:26.318
this concept of BMI.

00:16:26.418 --> 00:16:30.022
They said that
insurances cannot deny

00:16:30.122 --> 00:16:32.992
weight loss medication
based purely on the

00:16:33.092 --> 00:16:35.928
BMI. Now, that is
huge, and that's going

00:16:36.028 --> 00:16:38.597
to open the door for
many other patients to

00:16:38.697 --> 00:16:40.399
have access to this
drug.

00:16:40.799 --> 00:16:43.068
The big question is
whether the American

00:16:43.168 --> 00:16:45.204
insurance system can
support coverage for

00:16:45.304 --> 00:16:47.072
millions of people
needing these

00:16:47.172 --> 00:16:47.806
treatments in the
future.

00:16:48.407 --> 00:16:50.976
These two drugs are
going to have multiple

00:16:51.076 --> 00:16:53.946
benefits for patients
in a variety of health

00:16:54.046 --> 00:16:56.949
areas. So if that's
the case, I think we

00:16:57.049 --> 00:17:00.019
have to consider can
insurance afford all of

00:17:00.119 --> 00:17:02.521
this? And if they
can't, what do they do

00:17:02.621 --> 00:17:03.389
about it?

00:17:03.622 --> 00:17:04.957
Analysts predict that
competition among

00:17:05.057 --> 00:17:06.458
pharmaceutical
companies, along with

00:17:06.558 --> 00:17:09.261
availability, will
eventually drive prices

00:17:09.361 --> 00:17:10.229
down.

00:17:10.329 --> 00:17:13.632
The obesity treatments
will be available

00:17:13.732 --> 00:17:16.301
ultimately, you know,
certainly a decade or

00:17:16.402 --> 00:17:18.637
more from now for
pennies on the dollar.

00:17:18.737 --> 00:17:21.006
And so treating
obesity may become

00:17:21.106 --> 00:17:22.174
dramatically easier.

00:17:22.274 --> 00:17:24.309
To get there. Novo
Nordisk will first have

00:17:24.410 --> 00:17:26.645
to tackle quality
control on September

00:17:26.745 --> 00:17:29.748
21st, 2023, Reuters
reported the FDA had

00:17:29.848 --> 00:17:31.884
found manufacturing
shortfalls in the

00:17:31.984 --> 00:17:33.419
company's North
Carolina production

00:17:33.519 --> 00:17:36.355
plant in July that
could date back to May.

00:17:36.455 --> 00:17:38.524
Stocks fell by 3%.

00:17:38.624 --> 00:17:41.360
In a statement to
CNBC, Novo Nordisk said

00:17:41.460 --> 00:17:43.762
the FDA does hundreds
of routine inspections

00:17:43.862 --> 00:17:44.296
with all
pharmaceutical

00:17:44.863 --> 00:17:45.898
companies every year.

00:17:45.998 --> 00:17:48.033
Novo Nordisk has
responded to the FDA

00:17:48.133 --> 00:17:50.335
observations and the
facility continues to

00:17:50.436 --> 00:17:52.271
run and produce for
the market.

00:17:52.371 --> 00:17:55.040
Even if Novo Nordisk
and its peers can

00:17:55.140 --> 00:17:56.942
achieve the lofty goal
of helping those

00:17:57.042 --> 00:17:59.511
suffering from
obesity, there are some

00:17:59.611 --> 00:18:00.746
apprehensions.

00:18:00.846 --> 00:18:04.450
If Eli Lilly and Novo
Nordisk can continue to

00:18:04.550 --> 00:18:07.786
deliver and meet the
demand, then it could

00:18:07.886 --> 00:18:10.022
really change the
world. There is another

00:18:10.122 --> 00:18:13.492
risk. It could be
something completely

00:18:13.592 --> 00:18:17.162
different than just a
drug, but something you

00:18:17.262 --> 00:18:19.398
could use as you use
makeup.

00:18:19.898 --> 00:18:22.901
Maybe people would
forget to do exercise

00:18:23.001 --> 00:18:25.704
and to to eat healthy
because we simply take

00:18:25.804 --> 00:18:27.840
a drug. We are only
scratching the surface.

00:18:27.940 --> 00:18:30.676
And that's a little
bit scary, in fact.

00:18:30.776 --> 00:18:32.444
Still, according to the
company's leader, the

00:18:32.544 --> 00:18:33.745
attempt is worth the
risk.

00:18:34.613 --> 00:18:37.583
I think nowadays we
mankind is not

00:18:37.683 --> 00:18:39.451
struggling because of
infections, but I think

00:18:39.551 --> 00:18:41.019
we are struggling
because of of how we

00:18:41.120 --> 00:18:45.224
live. And with aging
populations, we see

00:18:45.324 --> 00:18:47.993
less and less
productive workers

00:18:48.093 --> 00:18:50.729
living with more and
more chronic diseases

00:18:50.829 --> 00:18:52.164
like cardiometabolic
diseases.

00:18:53.065 --> 00:18:56.368
And if we can address
that in in safe,

00:18:56.468 --> 00:18:58.837
efficacious ways, I
think that's good for

00:18:58.937 --> 00:19:01.240
all of us. I think
medical history will

00:19:01.340 --> 00:19:03.342
look back at
semaglutide as as one

00:19:03.442 --> 00:19:05.344
of the major
breakthroughs, a

00:19:05.444 --> 00:19:08.013
molecule that kept
giving, so to say.

